Бакалавриат
2025/2026
Введение в нейровизуализацию
Статус:
Курс обязательный (Когнитивная нейробиология)
Кто читает:
Базовая кафедра Института биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН
Где читается:
Факультет биологии и биотехнологии
Когда читается:
3-й курс, 4 модуль
Охват аудитории:
для своего кампуса
Язык:
английский
Кредиты:
4
Контактные часы:
40
Course Syllabus
Abstract
The course will outline and compare different optical microscopy techniques and super-resolution imaging in neuroscience. The course aims to teach students to understand basic principles of the current optical imaging techniques, microscope design, and image formation. The course will also offer laboratory practice in sample preparation, confocal imaging, and image analysis. Students will learn how to choose the most appropriate imaging method for their own research project. Topics also include clearing agents and techniques, optical imaging of brain activity in vivo, super-resolution imaging techniques, and applications for functional analyses of neuronal circuits.
Learning Objectives
- To provide students with knowledge and skills of various types of microscopy, to teach them to plan a correct microscopic experiment and obtain statistically significant data. During the course, students will independently perform a laboratory project on real brain samples.
Expected Learning Outcomes
- Demonstrate an understanding of the basic principles of geometric optics and optical image formation for the effective use of various microscopes.
- Know the principles of optical microscopy, including super-resolution microscopy, know and understand its application in neuroscience.
- Be able to present and discuss experimental data.
- Describe the application limitation of fluorescence microscopy, as well as specialized techniques such as FRET and FRAP, light-sheet microscopy.
- Understand how to set up and operate various types of microscopes to obtain high-quality images.
- Perform sample preparation for optical microscopy.
- Analyze and interpret microscopic images obtained using light sheet, confocal, and light microscopes for scientific research.
Course Contents
- Fundamentals of Microscopy. Geometrical and Wave Optics, Light.
- Optical Microscopy in Neuroscience. Overview of Modern Microscopy Methods
- Optical Microscopy in Neuroscience. Laboratory Work
Interim Assessment
- 2025/2026 4th module0.2 * Final Project + 0.3 * Laboratory Report + 0.2 * Presentation + 0.3 * Tests/Quiz
Bibliography
Recommended Core Bibliography
- Морозова, К. Н. Основы электронной микроскопии : учебное пособие для вузов / К. Н. Морозова. — 2-е изд. — Москва : Издательство Юрайт, 2022. — 84 с. — (Высшее образование). — ISBN 978-5-534-14415-4. — Текст : электронный // Образовательная платформа Юрайт [сайт]. — URL: https://urait.ru/bcode/496975 (дата обращения: 14.01.2026).
Recommended Additional Bibliography
- Багмут, А. Г., Багмут, И. А., Косевич, В. М., Николайчук, Г. П., & Резник, Н. А. (2016). Электронная микроскопия. НТУ “ХПИ.”
- Юрков, А. П. Биология. Электронная микроскопия биологических объектов : учебное пособие / А. П. Юрков, У. М. Маликов. — Санкт-Петербург : СПбГУТ им. М.А. Бонч-Бруевича, 2021. — 55 с. — ISBN 978-5-89160-214-4. — Текст : электронный // Лань : электронно-библиотечная система. — URL: https://e.lanbook.com/book/180010 (дата обращения: 00.00.0000). — Режим доступа: для авториз. пользователей.